Publications & Awards | 2014

Vorhagen S, Niessen CM
Mammalian aPKC/Par polarity complex mediated regulation of epithelial division orientation and cell fate
Exp Cell Res. 2014 Aug 13. [Epub ahead of print]

22 July 2014
Christian Günschmann was awarded the Research on Skin Dryness Award 2014 and the
8. Forschungspreis der AG Dermato-Endokrinologie der Arbeitsgemeinschaft Dermatologische Forschung e.V. (ADF) for the publication Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Günschmann C, Stachelscheid H, Akyüz MD, Schmitz A, Missero C, Brüning JC, Niessen CM. Dev Cell. 2013.

Willenborg S, Eckes B, Brinckmann J, Krieg T, Waisman A, Hartmann K, Roers A, Eming SA
Genetic ablation of mast cells redefines the role of mast cells in skin wound healing and bleomycin-induced fibrosis
J Invest Dermatol. 2014 Jul;134(7):2005-15

Rothe A, Jachimowicz RD, Borchmann S, Madlener M, Keßler J, Reiners KS, Sauer M, Hansen HP, Ullrich RT, Chatterjee S, Borchmann P, Yazaki P, Koslowsky TC, Engert A, Heukamp LC, Hallek M, von Strandmann EP
The bispecific immunoligand ULBP2-aCEA redirects natural killer cells to tumor cells and reveals potent anti-tumor activity against colon carcinoma
Int J Cancer. 2014 Jun 15;134(12):2829-40

Bald T, Landsberg J, Lopez-Ramos D, Renn M, Glodde N, Jansen P, Gaffal E, Steitz J, Tolba R, Kalinke U, Limmer A, Jönsson G, Hölzel M, Tüting T
Immune Cell-Poor Melanomas Benefit from PD-1 Blockade after Targeted Type I IFN Activation
Cancer Discov. 2014 Jun;4(6):674-87

Rinschen MM, Schermer B, Benzing T
Vasopressin-2 receptor signaling and autosomal dominant polycystic kidney disease: from bench to bedside and back again
J Am Soc Nephrol. 2014 Jun;25(6):1140-7

Chatterjee S, Wieczorek C, Schottle J, Siobal M, Hinze Y, Franz T, Florin A, Adamczak J, Heukamp L, Neumaier B, Ullrich RT
Transient anti-angiogenic treatment improves delivery of cytotoxic compounds and therapeutic outcome in lung cancer
Cancer Res. 2014 May 15;74(10):2816-24

Kohli P, Bartram MP, Habbig S, Pahmeyer C, Lamkemeyer T, Benzing T, Schermer B, Rinschen MM
Label-free quantitative proteomic analysis of the YAP/TAZ interactome
Am J Physiol Cell Physiol. 2014 May 1;306(9):C805-18

Lu X, Thomas RK, Peifer M
CGARS: cancer genome analysis by rank sums
Bioinformatics. 2014 May 1;30(9):1295-6

Coutelle O, Hornig-Do HT, Witt A, Andree M, Schiffmann LM, Piekarek M, Brinkmann K, Seeger JM, Liwschitz M, Miwa S, Hallek M, Krönke M, Trifunovic A, Eming SA, Wiesner RJ, Hacker UT, Kashkar H
Embelin inhibits endothelial mitochondrial respiration and impairs neoangiogenesis during tumor growth and wound healing
EMBO Mol Med. 2014 May 1;6(5):624-39

Hagmann H, Kuczkowski A, Ruehl M, Lamkemeyer T, Brodesser S, Horke S, Dryer S, Schermer B, Benzing T, Brinkkoetter PT
Breaking the chain at the membrane: paraoxonase 2 counteracts lipid peroxidation at the plasma membrane
FASEB J. 2014 Apr;28(4):1769-79

Fernandez-Cuesta L, Plenker D, Osada H, Sun R, Menon R, Leenders F, Ortiz-Cuaran S, Peifer M, Bos M, Dabler J, Malchers F, Schottle J, Vogel W, Dahmen I, Koker M, Ullrich RT, Wright GM, Russell PA, Wainer Z, Solomon B, Brambilla E, Nagy-Mignotte H, Moro-Sibilot D, Brambilla CG, Lantuejoul S, Altmuller J, Becker C, Nurnberg P, Heuckmann JM, Stoelben E, Petersen I, Clement JH, Sanger J, Muscarella LA, la Torre A, Fazio VM, Lahortiga I, Perera T, Ogata S, Parade M, Brehmer D, Vingron M, Heukamp LC, Buettner R, Zander T, Wolf J, Perner S, Ansen S, Haas SA, Yatabe Y, Thomas RK
CD74-NRG1 fusions in lung adenocarcinoma
Cancer Discov. 2014 Apr;4(4):415-22

Reiners KS, Dassler J, Coch C, Pogge von Strandmann E
Role of Exosomes Released by Dendritic Cells and/or by Tumor Targets: Regulation of NK Cell Plasticity
Front Immunol. 2014 Mar 7;5:91

Bald T, Quast T, Landsberg J, Rogava M, Glodde N, Lopez-Ramos D, Kohlmeyer J, Riesenberg S, van den Boorn-Konijnenberg D, Hömig-Hölzel C, Reuten R, Schadow B, Weighardt H, Wenzel D, Helfrich I, Schadendorf D, Bloch W, Bianchi ME, Lugassy C, Barnhill RL, Koch M, Fleischmann BK, Förster I, Kastenmüller W, Kolanus W, Hölzel M, Gaffal E, Tüting T
Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma
Nature. 2014 Mar 6;507(7490):109-13

Hansen HP, Engels HM, Dams M, Paes Leme AF, Pauletti BA, Simhadri VL, Dürkop H, Reiners KS, Barnert S, Engert A, Schubert R, Quondamatteo F, Hallek M, Pogge von Strandmann E
Protrusion-guided extracellular vesicles mediate CD30 trans-signalling in the microenvironment of Hodgkin's lymphoma
J Pathol. 2014 Mar;232(4):405-14

Brinkmann K, Hombach A, Seeger JM, Wagner-Stippich D, Klubertz D, Krönke M, Abken H, Kashkar H
Second mitochondria-derived activator of caspase mimetic (SMAC) potentiates tumor susceptibility toward natural killer cell-mediated killing
Leuk Lymphoma. 2014 Mar;55(3):645-51

Xue J, Schmidt SV, Sander J, Draffehn A, Krebs W, Quester I, De Nardo D, Gohel TD, Emde M, Schmidleithner L, Ganesan H, Nino-Castro A, Mallmann MR, Labzin L, Theis H, Kraut M, Beyer M, Latz E, Freeman TC, Ulas T, Schultze JL
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation
Immunity. 2014 Feb 20;40(2):274-88

Malchers F, Dietlein F, Schöttle J, Lu X, Nogova L, Albus K, Fernandez-Cuesta L, Heuckmann JM, Gautschi O, Diebold J, Plenker D, Gardizi M, Scheffler M, Bos M, Seidel D, Leenders F, Richters A, Peifer M, Florin A, Mainkar PS, Karre N, Chandrasekhar S, George J, Silling S, Rauh D, Zander T, Ullrich RT, Reinhardt HC, Ringeisen F, Büttner R, Heukamp LC, Wolf J, Thomas RK
Cell-autonomous and non-cell-autonomous mechanisms of transformation by amplified FGFR1 in lung cancer
Cancer Discov. 2014 Feb;4(2):246-57

Pallasch CP, Leskov I, Braun CJ, Vorholt D, Drake A, Soto-Feliciano YM, Bent EH, Schwamb J, Iliopoulou B, Kutsch N, van Rooijen N, Frenzel LP, Wendtner CM, Heukamp L, Kreuzer KA, Hallek M, Chen J, Hemann MT
Sensitizing protective tumor microenvironments to antibody-mediated therapy
Cell. 2014 Jan 30;156(3):590-602

Ma Y, Mattarollo SR, Adjemian S, Yang H, Aymeric L, Hannani D, Portela Catani JP, Duret H, Teng MW, Kepp O, Wang Y, Sistigu A, Schultze JL, Stoll G, Galluzzi L, Zitvogel L, Smyth MJ, Kroemer G
CCL2/CCR2-dependent recruitment of functional antigen-presenting cells into tumors upon chemotherapy
Cancer Res. 2014 Jan 15;74(2):436-45

Sommer D, Peters A, Wirtz T, Mai M, Ackermann J, Thabet Y, Schmidt J, Weighardt H, Wunderlich FT, Degen J, Schultze JL, Beyer M
Efficient genome engineering by targeted homologous recombination in mouse embryos using transcription activator-like effector nucleases
Nat Commun. 2014;5:3045

News

CRC832 Seminar Series
18 June 2014 | 5 pm (c.t.)
Changes in tissue and cellular organisation at early stages of colon cancer (Näthke I.)
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Publications
Transient anti-angiogenic treatment improves delivery of cytotoxic compounds and therapeutic outcome in lung cancer
(Chatterjee S. et al.)
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